1. Michelle Wu, Mayor

It’s not just that she’s the new mayor that makes Wu this year’s most influential Bostonian; it’s that she is a fundamentally new type of mayor. The city is changing over from old power structures to fresh ones, affecting everything from housing to contracting to development to policing and more. The first woman and person of color elected to Boston’s top job, Wu will oversee and direct this transition—probably for at least eight years, judging by history—creating new winners and losers, successes and failures, along the way. Several months into her term, we sat down in her office, a high-ceilinged enclave stocked with toys for her four- and seven-year-old boys, to talk about motherhood, the protesters who’ve disrupted her family’s life, and who’s really running things in Boston.